Mouse B7-DC/PD-L2/CD273 protein (Recombinant) (C-hFc) (STJP002804)

SKU:
STJP002804

£59.50 - £189.50
Current Stock:
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse B7-DC/PD-L2/CD273-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Mouse PD-L2 (Catalog: RP01585) at 10 Mu g/mL (100 Mu L/well) can bind Biotinylated Mouse PD-1 with a linear range of 19.5-622 ng/mL.
Gene Symbol: Pdcd1lg2
Gene ID: 58205
Uniprot ID: PD1L2_MOUSE
Immunogen Region: Leu20-Arg219
Immunogen: Recombinant Mouse B7-DC/PD-L2/CD273 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu20-Arg219) of mouse B7-DC/PD-L2/CD273 (Accession #NP_067371.1) fused with a hFc tag at the C-terminus.
Function Involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Protein Name Programmed Cell Death 1 Ligand 2
Pd-1 Ligand 2
Pd-L2
Pdcd1 Ligand 2
Programmed Death Ligand 2
Butyrophilin B7-Dc
B7-Dc
Cd Antigen Cd273
Database Links Reactome: R-MMU-389948
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Programmed Cell Death 1 Ligand 2 protein
Pd-1 Ligand 2 protein
Pd-L2 protein
Pdcd1 Ligand 2 protein
Programmed Death Ligand 2 protein
Butyrophilin B7-Dc protein
B7-Dc protein
Cd Antigen Cd273 protein
Pdcd1lg2 protein
B7dc protein
Btdc protein
Cd273 protein
Pdl2 protein

Information sourced from Uniprot.org

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