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Mouse B7-DC/PD-L2/CD273 protein (Recombinant) (C-hFc) (STJP002804)

Mouse B7-DC/PD-L2/CD273 protein (Recombinant) (C-hFc) (STJP002804)

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STJP002804

£59.50 - £189.50

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General Information
Product Properties
Target Information
Additional Info
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Host:	HEK293 cells
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Mouse B7-DC/PD-L2/CD273-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity:	Measured by its binding ability in a functional ELISA. Immobilized Mouse PD-L2 (Catalog: RP01585) at 10 Mu g/mL (100 Mu L/well) can bind Biotinylated Mouse PD-1 with a linear range of 19.5-622 ng/mL.

Gene Symbol:	Pdcd1lg2
Gene ID:	58205
Uniprot ID:	PD1L2_MOUSE
Immunogen Region:	Leu20-Arg219
Immunogen:	Recombinant Mouse B7-DC/PD-L2/CD273 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu20-Arg219) of mouse B7-DC/PD-L2/CD273 (Accession #NP_067371.1) fused with a hFc tag at the C-terminus.

Function	Involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Protein Name	Programmed Cell Death 1 Ligand 2 Pd-1 Ligand 2 Pd-L2 Pdcd1 Ligand 2 Programmed Death Ligand 2 Butyrophilin B7-Dc B7-Dc Cd Antigen Cd273
Database Links	Reactome: R-MMU-389948
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Programmed Cell Death 1 Ligand 2 protein Pd-1 Ligand 2 protein Pd-L2 protein Pdcd1 Ligand 2 protein Programmed Death Ligand 2 protein Butyrophilin B7-Dc protein B7-Dc protein Cd Antigen Cd273 protein Pdcd1lg2 protein B7dc protein Btdc protein Cd273 protein Pdl2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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