IBP160 Blocking Peptide peptide (STJ503682)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 1250-1300 on human RNA helicase aquarius protein.
General Information
| Short Description | IBP160 Blocking Peptide is synthetically produced from the 1250-1300 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | AQR |
| Gene ID | 9716 |
| Uniprot ID | AQR_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 1250-1300 on human RNA helicase aquarius protein. |
| Immunogen Region | 1250-1300 |
Additional Info
| Function | Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro). |
| Peptide Name | Rna Helicase AquariusIntron-Binding Protein Of 160 KdaIbp160 |
| Database Links | Reactome: R-HSA-6781823Reactome: R-HSA-6781827Reactome: R-HSA-6782135Reactome: R-HSA-6782210Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusNucleoplasmLocalizes To Speckle-Like Regions Of The Nucleoplasm |
| Alternative Peptide Names | Rna Helicase Aquarius proteinIntron-Binding Protein Of 160 Kda proteinIbp160 proteinAQR proteinKIAA0560 protein |
Information sourced from Uniprot.org