| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of 20mM HAc-NaAc, 150mM NaCl, 0.5% CHAPS, pH 6.0. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | WIF1 |
| Gene ID: | 11197 |
| Uniprot ID: | WIF1_HUMAN |
| Immunogen Region: | Gly29-Trp379Gln166Lys |
| Immunogen: | Recombinant Human WIF-1 (Q166K) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly29-Trp379 (Gln166Lys) ) of human WIF-1 (Accession #NP_009122.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | GPPQEESLYLWIDAHQARVL IGFEEDILIVSEGKMAPFTH DFRKAQQRMPAIPVNIHSMN FTWQAAGQAEYFYEFLSLRS LDKGIMADPTVNVPLLGTVP HKASVVQVGFPCLGKQDGVA AFEVDVIVMNSEGNTILKTP QNAIFFKTCQQAECPGGCRN GGFCNERRICECPDGFHGPH CEKALCTPRCMNGGLCVTPG FCICPPGFYGVNCDKANCST TCFNGGTCFYPGKCICPPG |
| Function | Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. |
| Protein Name | Wnt Inhibitory Factor 1Wif-1 |
| Database Links | Reactome: R-HSA-201681Reactome: R-HSA-3772470 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Wnt Inhibitory Factor 1 proteinWif-1 proteinWIF1 proteinUNQ191 proteinPRO217 protein |
Information sourced from Uniprot.org