Human VOPP1 protein (Recombinant) (His-Tag) (STJP017211)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017211
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General Information

Short DescriptionRecombinant-Human VOPP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% Glycerol, 0.2M NaCl
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolVOPP1
Gene ID81552
Uniprot IDVOPP1_HUMAN
Accession NumberNP_110423.3
ImmunogenHuman
Immunogen Region82-172aa
Immunogen SequenceRRRMYPPPL IEEPAFNVSY TRQPPNPGPG AQQPGPPYYT DPGGPGMNPV GNSMAMAFQV PPNSPQGSVA CPPPPAYCNT PPPPYEQVVK AK

Additional Info

Tissue Specificity Widely expressed with highest levels in thymus and ovary.
Function Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. May sequester WWOX in lysosomal vesicles and thereby regulate WWOX role as tumor suppressor.
Protein Name Ww Domain Binding Protein Vopp1
Egfr-Coamplified And Overexpressed Protein
Ecop
Glioblastoma-Amplified Secreted Protein
Putative Nf-Kappa-B-Activating Protein 055n
Vesicular - Overexpressed In Cancer - Prosurvival Protein 1
Database Links
Cellular Localisation Cytoplasmic Vesicle Membrane
Single-Pass Type I Membrane Protein
Late Endosome Membrane
Single-Pass Membrane Protein
Lysosome Membrane
When Overexpressed
Localizes In The Nucleus And Perinuclear Regions
Alternative Protein Names Ww Domain Binding Protein Vopp1 protein
Egfr-Coamplified And Overexpressed Protein protein
Ecop protein
Glioblastoma-Amplified Secreted Protein protein
Putative Nf-Kappa-B-Activating Protein 055n protein
Vesicular - Overexpressed In Cancer - Prosurvival Protein 1 protein
VOPP1 protein
ECOP protein
GASP protein

Information sourced from Uniprot.org

Citations

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