Human TSPYL2 protein (Recombinant) (N-His) (STJP010991)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human TSPYL2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | TSPYL2 |
| Gene ID | 64061 |
| Uniprot ID | TSYL2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Pro263-Arg418 |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation. |
| Function | Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. |
| Protein Name | Testis-Specific Y-Encoded-Like Protein 2Tspy-Like Protein 2Cell Division Autoantigen 1Cutaneous T-Cell Lymphoma-Associated Antigen Se20-4Ctcl-Associated Antigen Se20-4Differentially-Expressed Nucleolar Tgf-Beta1 Target ProteinNuclear Protein Of 79 KdaNp79 |
| Database Links | Reactome: R-HSA-381038 |
| Cellular Localisation | NucleusCytoplasmEnriched In Transcriptionally Active Regions Of Chromatin In Neurons |
| Alternative Protein Names | Testis-Specific Y-Encoded-Like Protein 2 proteinTspy-Like Protein 2 proteinCell Division Autoantigen 1 proteinCutaneous T-Cell Lymphoma-Associated Antigen Se20-4 proteinCtcl-Associated Antigen Se20-4 proteinDifferentially-Expressed Nucleolar Tgf-Beta1 Target Protein proteinNuclear Protein Of 79 Kda proteinNp79 proteinTSPYL2 proteinCDA1 proteinDENTT proteinTSPX proteinHRIHFB2216 protein |
Information sourced from Uniprot.org