| Short Description : | Recombinant-Human Troponin C2/TNNC2-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 100mM NaCl, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TNNC2 |
| Gene ID: | 7125 |
| Uniprot ID: | TNNC2_HUMAN |
| Accession Number: | NP_003270.1 |
| Immunogen: | Human |
| Immunogen Region: | 1-160aa |
| Immunogen Sequence: | MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ |
| Function | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. |
| Protein Name | Troponin C - Skeletal Muscle |
| Database Links | Reactome: R-HSA-390522 |
| Cellular Localisation | |
| Alternative Protein Names | Troponin C - Skeletal Muscle proteinTNNC2 protein |
Information sourced from Uniprot.org
