Human Troponin T protein (Recombinant) (His-Tag) (STJP016474)

Name: Human Troponin T protein (Recombinant) (His-Tag) (STJP016474)
SKU: STJP016474
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP016474

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Human Troponin T-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.25 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 50% Glycerol, 0.5M NaCl, 0.1mM PMSF, 1mM DTT, 100mM imidazole
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	TNNT2
Gene ID	7139
Uniprot ID	TNNT2_HUMAN
Accession Number	NP_001001431.1
Immunogen	Human
Immunogen Region	1-285aa
Immunogen Sequence	MSDIEEVVEE YEEEEQEEAA VEEQEEAAEE DAEAEAETEE TRAEEDEEEE EAKEAEDGPM EESKPKPRSF MPNLVPPKIP DGERVDFDDI HRKRMEKDLN ELQALIEAHF ENRKKEEEEL VSLKDRIERR RAERAEQQRI RNEREKERQN RLAEERARRE EEENRRKAED EARKKKALSN MMHFGGYIQK TERKSGKRQT EREKKK

Tissue Specificity	Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
Post Translational Modifications	Phosphorylation at Thr-213 by PRKCA induces significant reduction in myofilament calcium sensitivity and actomyosin ATPase activity.
Function	Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Protein Name	Troponin T - Cardiac Muscle Tntc Cardiac Muscle Troponin T Ctnt
Database Links	Reactome: R-HSA-390522
Cellular Localisation
Alternative Protein Names	Troponin T - Cardiac Muscle protein Tntc protein Cardiac Muscle Troponin T protein Ctnt protein TNNT2 protein

Information sourced from Uniprot.org