Human TNFRSF17/BCMA/CD269 protein (Recombinant) (C-His&Avi) {Biotin} (STJP020027)
SPECIFICATIONS
HostHEK293 cells
ConjugationBiotin
ImmunogenBiotinylated Recombinant Human TNFRSF17/BCMA/CD269 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ala54) of Human TNFRSF17/BCMA/CD269 (Accession #Q02223-1) fused with a C-His&Avi tag at the
General Information
| Short Description | Recombinant-Human TNFRSF17/BCMA/CD269-C-His&Avi protein was developed in hek293 cells using the region Met1-Ala54. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | TNFRSF17 |
| Gene ID | 608 |
| Uniprot ID | TNR17_HUMAN |
| Immunogen | Biotinylated Recombinant Human TNFRSF17/BCMA/CD269 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ala54) of Human TNFRSF17/BCMA/CD269 (Accession #Q02223-1) fused with a C-His&Avi tag at the |
| Immunogen Region | Met1-Ala54 |
| Immunogen Sequence | MLQMAGQCSQNEYFDSLLHA CIPCQLRCSSNTPPLTCQRY CNASVTNSVKGTNA |
Additional Info
| Tissue Specificity | Expressed in mature B-cells, but not in T-cells or monocytes. |
| Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 17B-Cell Maturation ProteinCd Antigen Cd269 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane ProteinEndomembrane SystemPerinuclear Golgi-Like Structures |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 17 proteinB-Cell Maturation Protein proteinCd Antigen Cd269 proteinTNFRSF17 proteinBCM proteinBCMA protein |
Information sourced from Uniprot.org