| Host: | HEK293 Cells |
| Applications: | SDS-PAGE/Bioactivity |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human Thrombopoietin-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Concentration: | 0.25 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity: | Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 range ≤10 ng/ml. |
| Gene Symbol: | THPO |
| Gene ID: | 7066 |
| Uniprot ID: | TPO_HUMAN |
| Immunogen Region: | 22-353aa |
| Accession Number: | NP_000451.1 |
| Immunogen: | Human |
| Immunogen Sequence: |
| Function | Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
| Protein Name | ThrombopoietinC-Mpl LigandMlMegakaryocyte Colony-Stimulating FactorMegakaryocyte Growth And Development FactorMgdfMyeloproliferative Leukemia Virus Oncogene Ligand |
| Database Links | Reactome: R-HSA-76009 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Thrombopoietin proteinC-Mpl Ligand proteinMl proteinMegakaryocyte Colony-Stimulating Factor proteinMegakaryocyte Growth And Development Factor proteinMgdf proteinMyeloproliferative Leukemia Virus Oncogene Ligand proteinTHPO proteinMGDF protein |
Information sourced from Uniprot.org
