| Host: | E.coli |
| Applications: | SDS-PAGE/Denatured |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human STOM-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STOM |
| Gene ID: | 2040 |
| Uniprot ID: | STOM_HUMAN |
| Immunogen Region: | 55-288aa |
| Accession Number: | NP_004090 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSKIIKEYE RAIIFRLGRI LQGGAKGPGL FFILPCTDSF IKVDMRTISF DIPPQEILTK DSVTISVDGV VYYRVQNATL AVANITNADS ATRLLAQTTL RNVLGTKNLS QILSDREEIA HNMQSTLDDA TDAWGIKVER VEIKDVKLPV QLQRAMAAEA EASREARAKV IAAEGEMNAS RALKEASMVI TESPAALQLR YLQTLTTI |
| Tissue Specificity | Detected in erythrocytes (at protein level). Widely expressed. |
| Function | Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity. |
| Protein Name | StomatinErythrocyte Band 7 Integral Membrane ProteinErythrocyte Membrane Protein Band 7.2Protein 7.2b |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013406Reactome: R-HSA-9013407Reactome: R-HSA-9013409 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonLipid-AnchorMembrane RaftMelanosomeCytoplasmic VesicleLocalizes To Juxtanuclear Structure Probably Derived From The Golgi ApparatusColocalizes With Cortical Actin Microfilaments At Small Plasma Membrane ProtrusionsAssociates With Alpha-Granular Lipid RaftsTranslocates From The Alpha-Granular Lipid Rafts To The Cell Membrane On Thrombin Activation And Selectively Enriched In Released MicrovesiclesIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Protein Names | Stomatin proteinErythrocyte Band 7 Integral Membrane Protein proteinErythrocyte Membrane Protein Band 7.2 proteinProtein 7.2b proteinSTOM proteinBND7 proteinEPB72 protein |
Information sourced from Uniprot.org