• Human SR-D1/CD68 protein (Recombinant) (C-raFc) (STJP001520)

Human SR-D1/CD68 protein (Recombinant) (C-raFc) (STJP001520)

SKU:
STJP001520

Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human SR-D1/CD68-C-raFc protein was developed from hek293 cells and has a target region of C-raFc. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Gene Symbol: CD68
Gene ID: 968
Uniprot ID: CD68_HUMAN
Immunogen: Recombinant Human SR-D1/CD68 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asn22-Ser319) of human SR-D1/CD68 (Accession #NP_001242.2) fused with a raFc tag at the C-terminus.
Post Translational Modifications N- and O-glycosylated.
Function Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Protein Name Macrosialin
Gp110
Cd Antigen Cd68
Database Links Reactome: R-HSA-6798695
Cellular Localisation Isoform Short: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform Long: Endosome Membrane
Lysosome Membrane
Alternative Protein Names Macrosialin protein
Gp110 protein
Cd Antigen Cd68 protein
CD68 protein

Information sourced from Uniprot.org

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