| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
<0.1 EU/Mu g |
| Gene Symbol: |
CD68 |
| Gene ID: |
968 |
| Uniprot ID: |
CD68_HUMAN |
| Immunogen: |
Recombinant Human SR-D1/CD68 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asn22-Ser319) of human SR-D1/CD68 (Accession #NP_001242.2) fused with a raFc tag at the C-terminus. |
| Immunogen Sequence: |
NDCPHKKSATLLPSFTVTPT VTESTGTTSHRTTKSHKTTT HRTTTTGTTSHGPTTATHNP TTTSHGNVTVHPTSNSTATS QGPSTATHSPATTSHGNATV HPTSNSTATSPGFTSSAHPE PPPPSPSPSPTSKETIGDYT WTNGSQPCVHLQAQIQIRVM YTTQGGGEAWGISVLNPNKT KVQGSCEGAHPHLLLSFPYG HLSFGFMQDLQQKVVYLSYM AVEYNVSFPHAAQWTFSAQ |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. |
| Protein Name | MacrosialinGp110Cd Antigen Cd68 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Isoform Short: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Long: Endosome MembraneLysosome Membrane |
| Alternative Protein Names | Macrosialin proteinGp110 proteinCd Antigen Cd68 proteinCD68 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
