Human SLIT1 protein (Recombinant) (N-His) (STJP003335)

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STJP003335
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SLIT1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SLIT1
Gene ID: 6585
Uniprot ID: SLIT1_HUMAN
Immunogen Region: Asn647-Arg835
Immunogen: Homo sapiens (Human)
Function Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 together seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb.
Protein Name Slit Homolog 1 Protein
Slit-1
Multiple Epidermal Growth Factor-Like Domains Protein 4
Multiple Egf-Like Domains Protein 4
Database Links Reactome: R-HSA-373752
Reactome: R-HSA-376176
Reactome: R-HSA-428542
Reactome: R-HSA-8985801
Reactome: R-HSA-9010553
Cellular Localisation Secreted
Alternative Protein Names Slit Homolog 1 Protein protein
Slit-1 protein
Multiple Epidermal Growth Factor-Like Domains Protein 4 protein
Multiple Egf-Like Domains Protein 4 protein
SLIT1 protein
KIAA0813 protein
MEGF4 protein
SLIL1 protein

Information sourced from Uniprot.org

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