Human SLC13A2 protein (Recombinant) (N-His-KSI) (STJP016217)

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STJP016217
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human SLC13A2-N-His-KSI protein was developed from e.coli and has a target region of N-His-KSI. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: SLC13A2
Gene ID: 9058
Uniprot ID: S13A2_HUMAN
Immunogen Region: Phe134-Met221
Immunogen: Homo sapiens (Human)
Function Low-affinity sodium-dicarboxylate cotransporter, that mediates the entry of citric acid cycle intermediates, such as succinate, citrate, fumarate and alpha-ketoglutarate (2-oxoglutarate) into the small intestine and renal proximal tubule. Transports the dicarboxylate into the cell with a probable stoichiometry of 3 Na(+) for 1 divalent dicarboxylate, rendering the process electrogenic. Citrate is transported in protonated form as a divalent anion, rather than the trivalent form which is normally found in blood. Has a critical role in renal dicarboxylate transport.
Protein Name Solute Carrier Family 13 Member 2
Na(+/Dicarboxylate Cotransporter 1
Nadc-1
Renal Sodium/Dicarboxylate Cotransporter
Database Links Reactome: R-HSA-433137
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Solute Carrier Family 13 Member 2 protein
Na(+/Dicarboxylate Cotransporter 1 protein
Nadc-1 protein
Renal Sodium/Dicarboxylate Cotransporter protein
SLC13A2 protein
NADC1 protein
SDCT1 protein

Information sourced from Uniprot.org

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