• Human Serum albumin/ALB protein (Recombinant) (C-His) (STJP001024)

Human Serum albumin/ALB protein (Recombinant) (C-His) (STJP001024)

SKU:
STJP001024

Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Serum albumin/ALB-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Gene Symbol: ALB
Gene ID: 213
Uniprot ID: ALBU_HUMAN
Immunogen: Recombinant Human Serum albumin/ALB Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp 25-Leu 609 ) of human Serum albumin (Accession #NP_000468.1) fused with a 6×His tag at the C-terminus.
Post Translational Modifications Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606. Glycated in diabetic patients. Phosphorylated by FAM20C in the extracellular medium. Acetylated on Lys-223 by acetylsalicylic acid.
Function Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin.
Protein Name Albumin
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-159418
Reactome: R-HSA-189451
Reactome: R-HSA-189483
Reactome: R-HSA-2168880
Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Reactome: R-HSA-8964058
Reactome: R-HSA-9707564
Reactome: R-HSA-9749641
Reactome: R-HSA-9757110
Reactome: R-HSA-9793528
Cellular Localisation Secreted
Alternative Protein Names Albumin protein
ALB protein
GIG20 protein
GIG42 protein
PRO0903 protein
PRO1708 protein
PRO2044 protein
PRO2619 protein
PRO2675 protein
UNQ696 protein
PRO1341 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance