| Short Description : | Recombinant-Human Sepiapterin reductase/SPR-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Gene Symbol: | SPR |
| Gene ID: | 6697 |
| Uniprot ID: | SPRE_HUMAN |
| Accession Number: | NP_003115 |
| Immunogen: | Human |
| Immunogen Region: | 1-261aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MEGGLGRAVC LLTGASRGFG RTLAPLLASL LSPGSVLVLS ARNDEALRQL EAELGAERSG LRVVRVPADL GAEAGLQQLL GALRELPRPK GLQRLLLINN AGSLGDVSKG FVDLSDSTQV NNYWALNLTS MLCLTSSVLK AFPDSPGLNR TVVNISSLCA LQPFKGWALY CAGKAARDML FQVLALEEPN VRVLNYAPGP LDTDMQQL |
| Post Translational Modifications | In vitro phosphorylation of Ser-213 by CaMK2 does not change kinetic parameters. |
| Function | Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin. |
| Protein Name | Sepiapterin ReductaseSpr |
| Database Links | Reactome: R-HSA-1474151Reactome: R-HSA-203615 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Sepiapterin Reductase proteinSpr proteinSPR protein |
Information sourced from Uniprot.org
