Human RNF13 protein (Recombinant) (N-His) (STJP010675)

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STJP010675
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human RNF13-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: RNF13
Gene ID: 11342
Uniprot ID: RNF13_HUMAN
Immunogen Region: Glu33-Glu175
Immunogen: Homo sapiens (Human)
Post Translational Modifications Autoubiquitinated.
Function E3 ubiquitin-protein ligase that regulates cell proliferation. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA. Also involved in protein trafficking and localization.
Protein Name E3 Ubiquitin-Protein Ligase Rnf13
Ring Finger Protein 13
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Late Endosome Membrane
Lysosome Membrane
Nucleus Inner Membrane
Under Certain Conditions
Relocalizes To Recycling Endosomes And To The Inner Nuclear Membrane
Alternative Protein Names E3 Ubiquitin-Protein Ligase Rnf13 protein
Ring Finger Protein 13 protein
RNF13 protein
RZF protein

Information sourced from Uniprot.org

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