| Short Description : | Recombinant-Human Ribonuclease A/RNASE 1-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Enzyme Activity |
| Host: | HEK293 Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity: | Specific activity is > 5 X 10^4 unit/mg, and is defined as the amount of enzyme that cleaves 1.0 pmole of RNase probe per minute at 25C. |
| Gene Symbol: | RNASE1 |
| Gene ID: | 6035 |
| Uniprot ID: | RNAS1_HUMAN |
| Accession Number: | NP_937878.1 |
| Immunogen: | Human |
| Immunogen Region: | 29-156aa |
| Immunogen Sequence: | KESRAKKFQR QHMDSDSSPS SSSTYCNQMM RRRNMTQGRC KPVNTFVHEP LVDVQNVCFQ EKVTCKNGQG NCYKSNSSMH ITDCRLTNGS RYPNCAYRTS PKERHIIVAC EGSPYVPVHF DASVEDST |
| Tissue Specificity | Pancreas and other tissues and body fluids (indicating it may have other physiological functions besides its role in digestion). |
| Post Translational Modifications | N-linked glycans are of complex type. |
| Function | Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA. |
| Protein Name | Ribonuclease PancreaticHp-RnaseRib-1Rnase Upi-1Ribonuclease 1Rnase 1Ribonuclease ARnase A |
| Database Links | Reactome: R-HSA-9613829Reactome: R-HSA-9615710Reactome: R-HSA-9925561 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Ribonuclease Pancreatic proteinHp-Rnase proteinRib-1 proteinRnase Upi-1 proteinRibonuclease 1 proteinRnase 1 proteinRibonuclease A proteinRnase A proteinRNASE1 proteinRIB1 proteinRNS1 protein |
Information sourced from Uniprot.org