Human PSRC1 protein (Recombinant) (N-His-KSI) (STJP016042)

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STJP016042
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PSRC1-N-His-KSI protein was developed from e.coli for the region N-His-KSI. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: PSRC1
Gene ID: 84722
Uniprot ID: PSRC1_HUMAN
Immunogen Region: Glu2-Arg363
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated during mitosis.
Function Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression.
Protein Name Proline/Serine-Rich Coiled-Coil Protein 1
Database Links
Cellular Localisation Cytoplasm
Cytoskeleton
Spindle
Spindle Pole
Detected At The Mitotic Spindle And Spindle Poles
Diffusely Distributed Throughout The Cell During Interphase
Alternative Protein Names Proline/Serine-Rich Coiled-Coil Protein 1 protein
PSRC1 protein
DDA3 protein
FP3214 protein

Information sourced from Uniprot.org

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