• Human PSMA/FOLH1 protein (Recombinant) (N-hFc) (STJP002392)
  • Human PSMA/FOLH1 protein (Recombinant) (N-hFc) (STJP002392)
  • Human PSMA/FOLH1 protein (Recombinant) (N-hFc) (STJP002392)
  • Human PSMA/FOLH1 protein (Recombinant) (N-hFc) (STJP002392)

Human PSMA/FOLH1 protein (Recombinant) (N-hFc) (STJP002392)

SKU:
STJP002392-100

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Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human PSMA/FOLH1-N-hFc protein was developed from hek293 cells and has a target region of N-hFc. For use in research applications.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FOLH1
Gene ID: 2346
Uniprot ID: FOLH1_HUMAN
Immunogen Region: Lys44-Ala750
Immunogen: Recombinant Human PSMA/FOLH1 Protein is expressed from Expi293 with hFc tag at the N-terminal.;It contains Lys44-Ala750.
Post Translational Modifications The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis. The N-terminus is blocked.
Function Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
Protein Name Glutamate Carboxypeptidase 2
Cell Growth-Inhibiting Gene 27 Protein
Folate Hydrolase 1
Folylpoly-Gamma-Glutamate Carboxypeptidase
Fgcp
Glutamate Carboxypeptidase Ii
Gcpii
Membrane Glutamate Carboxypeptidase
Mgcp
N-Acetylated-Alpha-Linked Acidic Dipeptidase I
Naaladase I
Prostate-Specific Membrane Antigen
Psm
Psma
Pteroylpoly-Gamma-Glutamate Carboxypeptidase
Database Links Reactome: R-HSA-8963693
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Isoform Psma': Cytoplasm
Alternative Protein Names Glutamate Carboxypeptidase 2 protein
Cell Growth-Inhibiting Gene 27 Protein protein
Folate Hydrolase 1 protein
Folylpoly-Gamma-Glutamate Carboxypeptidase protein
Fgcp protein
Glutamate Carboxypeptidase Ii protein
Gcpii protein
Membrane Glutamate Carboxypeptidase protein
Mgcp protein
N-Acetylated-Alpha-Linked Acidic Dipeptidase I protein
Naaladase I protein
Prostate-Specific Membrane Antigen protein
Psm protein
Psma protein
Pteroylpoly-Gamma-Glutamate Carboxypeptidase protein
FOLH1 protein
FOLH protein
NAALAD1 protein
PSM protein
PSMA protein
GIG27 protein

Information sourced from Uniprot.org

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