Human PSMA/FOLH1 protein (Recombinant) (N-hFc) (STJP002392)

SKU:

STJP002392-100

£382.50

General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human PSMA/FOLH1-N-hFc protein was developed from hek293 cells and has a target region of N-hFc. For use in research applications.

Storage Instruction:

Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FOLH1
Gene ID:	2346
Uniprot ID:	FOLH1_HUMAN
Immunogen Region:	Lys44-Ala750
Immunogen:	Recombinant Human PSMA/FOLH1 Protein is expressed from Expi293 with hFc tag at the N-terminal.；It contains Lys44-Ala750.

Post Translational Modifications	The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis. The N-terminus is blocked.
Function	Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
Protein Name	Glutamate Carboxypeptidase 2 Cell Growth-Inhibiting Gene 27 Protein Folate Hydrolase 1 Folylpoly-Gamma-Glutamate Carboxypeptidase Fgcp Glutamate Carboxypeptidase Ii Gcpii Membrane Glutamate Carboxypeptidase Mgcp N-Acetylated-Alpha-Linked Acidic Dipeptidase I Naaladase I Prostate-Specific Membrane Antigen Psm Psma Pteroylpoly-Gamma-Glutamate Carboxypeptidase
Database Links	Reactome: R-HSA-8963693
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein Isoform Psma': Cytoplasm
Alternative Protein Names	Glutamate Carboxypeptidase 2 protein Cell Growth-Inhibiting Gene 27 Protein protein Folate Hydrolase 1 protein Folylpoly-Gamma-Glutamate Carboxypeptidase protein Fgcp protein Glutamate Carboxypeptidase Ii protein Gcpii protein Membrane Glutamate Carboxypeptidase protein Mgcp protein N-Acetylated-Alpha-Linked Acidic Dipeptidase I protein Naaladase I protein Prostate-Specific Membrane Antigen protein Psm protein Psma protein Pteroylpoly-Gamma-Glutamate Carboxypeptidase protein FOLH1 protein FOLH protein NAALAD1 protein PSM protein PSMA protein GIG27 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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