| Function | Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 3bHepatic Glycogen-Targeting Protein Phosphatase 1 Regulatory Subunit GlProtein Phosphatase 1 Regulatory Subunit 4Pp1 Subunit R4Protein Phosphatase 1 Subunit GlPtg |
| Database Links | |
| Cellular Localisation | |
| Alternative Protein Names | Protein Phosphatase 1 Regulatory Subunit 3b proteinHepatic Glycogen-Targeting Protein Phosphatase 1 Regulatory Subunit Gl proteinProtein Phosphatase 1 Regulatory Subunit 4 proteinPp1 Subunit R4 proteinProtein Phosphatase 1 Subunit Gl proteinPtg proteinPPP1R3B proteinPPP1R4 protein |
Information sourced from Uniprot.org
