Human PPP1R3B protein (Recombinant) (N-His) (STJP014766)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PPP1R3B-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for this information. |
Target Information
| Gene Symbol | PPP1R3B |
| Gene ID | 79660 |
| Uniprot ID | PPR3B_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Tyr284 |
Additional Info
| Function | Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 3bHepatic Glycogen-Targeting Protein Phosphatase 1 Regulatory Subunit GlProtein Phosphatase 1 Regulatory Subunit 4Pp1 Subunit R4Protein Phosphatase 1 Subunit GlPtg |
| Database Links | |
| Cellular Localisation | |
| Alternative Protein Names | Protein Phosphatase 1 Regulatory Subunit 3b proteinHepatic Glycogen-Targeting Protein Phosphatase 1 Regulatory Subunit Gl proteinProtein Phosphatase 1 Regulatory Subunit 4 proteinPp1 Subunit R4 proteinProtein Phosphatase 1 Subunit Gl proteinPtg proteinPPP1R3B proteinPPP1R4 protein |
Information sourced from Uniprot.org