Function | Mitochondrial phosphoenolpyruvate carboxykinase that catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Can play an active role in glyceroneogenesis and gluconeogenesis. |
Protein Name | Phosphoenolpyruvate Carboxykinase Gtp - MitochondrialPepck-MPhosphoenolpyruvate Carboxykinase 2 - MitochondrialMtpck2 |
Database Links | Reactome: R-HSA-70263 |
Cellular Localisation | Mitochondrion |
Alternative Protein Names | Phosphoenolpyruvate Carboxykinase Gtp - Mitochondrial proteinPepck-M proteinPhosphoenolpyruvate Carboxykinase 2 - Mitochondrial proteinMtpck2 proteinPCK2 proteinPEPCK2 protein |
Information sourced from Uniprot.org