Human OS9 protein (Recombinant) (N-His) (STJP007740)

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STJP007740
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Short Description :Recombinant-Human OS9-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:OS9
Gene ID:10956
Uniprot ID:OS9_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Asn32-Gln251
Post Translational Modifications Intramolecular disulfide bonds. Isoform 1 and isoform 2 are N-glycosylated.
Function Lectin component of the HRD1 complex, which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). Specifically recognizes and binds improperly folded glycoproteins as well as hyperglycosylated proteins, retain them in the ER, and transfers them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 as well as hyperglycosylated HSP90B1.
Protein Name Protein Os-9
Amplified In Osteosarcoma 9
Database Links Reactome: R-HSA-382556
Reactome: R-HSA-5358346
Reactome: R-HSA-5362768
Reactome: R-HSA-5678895
Reactome: R-HSA-901032
Cellular Localisation Endoplasmic Reticulum Lumen
Alternative Protein Names Protein Os-9 protein
Amplified In Osteosarcoma 9 protein
OS9 protein

Information sourced from Uniprot.org

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