Human OS9 protein (Recombinant) (N-His) (STJP007740)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human OS9-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | OS9 |
| Gene ID | 10956 |
| Uniprot ID | OS9_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn32-Gln251 |
Additional Info
| Post Translational Modifications | Intramolecular disulfide bonds. Isoform 1 and isoform 2 are N-glycosylated. |
| Function | Lectin component of the HRD1 complex, which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). Specifically recognizes and binds improperly folded glycoproteins as well as hyperglycosylated proteins, retain them in the ER, and transfers them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 as well as hyperglycosylated HSP90B1. |
| Protein Name | Protein Os-9Amplified In Osteosarcoma 9 |
| Database Links | Reactome: R-HSA-382556Reactome: R-HSA-5358346Reactome: R-HSA-5362768Reactome: R-HSA-5678895Reactome: R-HSA-901032 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Protein Names | Protein Os-9 proteinAmplified In Osteosarcoma 9 proteinOS9 protein |
Information sourced from Uniprot.org