Human NUBP1 protein (Recombinant) (His-Tag) (STJP019131)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human NUBP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NUBP1 |
| Gene ID | 4682 |
| Uniprot ID | NUBP1_HUMAN |
| Accession Number | NP_002475.2 |
| Immunogen | Human |
| Immunogen Region | 1-320aa |
| Immunogen Sequence |
Additional Info
| Function | Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure. |
| Protein Name | Cytosolic Fe-S Cluster Assembly Factor Nubp1Nucleotide-Binding Protein 1Nbp 1 |
| Database Links | Reactome: R-HSA-2564830 |
| Cellular Localisation | CytoplasmNucleusCell ProjectionCytoskeletonCilium AxonemeCilium Basal BodyMicrotubule Organizing CenterCentrosomeCentrioleEnriched In Centrioles Of Microtubule Asters During ProphasePrometaphase And Telophase Stages Of MitosisLocalized At Centrioles And In The Nucleus At InterphaseColocalizes With Nubp-2 At PrometaphaseSpecifically Localizes To The Axenome Of Motile Cilia As Opposed To Primary Non-Motile CiliaLocalization Is Independent Of Nubp2 And Kifc1 |
| Alternative Protein Names | Cytosolic Fe-S Cluster Assembly Factor Nubp1 proteinNucleotide-Binding Protein 1 proteinNbp 1 proteinNUBP1 proteinNBP proteinNBP1 protein |
Information sourced from Uniprot.org