| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: |
NLGN3 |
| Gene ID: |
54413 |
| Uniprot ID: |
NLGN3_HUMAN |
| Immunogen: |
Recombinant Human Neuroligin-3/NLGN3 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gln 38-Ser 689 ) of human Neuroligin 3/NLGN3 (Accession #NP_061850.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: |
QAPAPTVNTHFGKLRGARVP LPSEILGPVDQYLGVPYAAP PIGEKRFLPPEPPPYWSGIR NATHFPPVCPQNIHTAVPEV MLPVWFTANLDIVATYIQEP NEDCLYLNVYVPTEDGSGAK KQGEDLADNDGDEDEDIRDS GAKPVMVYIHGGSYMEGTGN MIDGSILASYGNVIVITLNY RVGVLGFLSTGDQAAKGNYG LLDQIQALRWVSENIAFFGG DPRRITVFGSGIGASCVSL |
| Function | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. |
| Protein Name | Neuroligin-3Gliotactin Homolog |
| Database Links | Reactome: R-HSA-6794361 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSynapseDetected At Both Glutamatergic And Gabaergic Synapses |
| Alternative Protein Names | Neuroligin-3 proteinGliotactin Homolog proteinNLGN3 proteinKIAA1480 proteinNL3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
