| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | |
| Function | Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. |
| Protein Name | Neuroepithelial Cell-Transforming Gene 1 ProteinProto-Oncogene P65 Net1Rho Guanine Nucleotide Exchange Factor 8 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-8980692Reactome: R-HSA-9013026 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative ELISA Names | Neuroepithelial Cell-Transforming Gene 1 Protein ELISA kitProto-Oncogene P65 Net1 ELISA kitRho Guanine Nucleotide Exchange Factor 8 ELISA kitNET1 ELISA kitARHGEF8 ELISA kit |
| output | |
Information sourced from Uniprot.org