Human NDNF protein (Recombinant) (N-GST) (STJP005739)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NDNF-N-GST protein was developed from e.coli for the region N-GST. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | NDNF |
| Gene ID | 79625 |
| Uniprot ID | NDNF_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met238-Phe331 |
Additional Info
| Post Translational Modifications | O-glycosylated.contains heparan sulfate and chondroitin sulfate. N-glycosylated. |
| Function | Secretory protein that plays a role in various cellular processes. Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus. Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system. May also act through the regulation of growth factors activity and downstream signaling. Also regulates extracellular matrix assembly and cell adhesiveness. Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms. |
| Protein Name | Protein NdnfNeuron-Derived Neurotrophic Factor |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Protein Ndnf proteinNeuron-Derived Neurotrophic Factor proteinNDNF proteinC4orf31 proteinUNQ2748 proteinPRO6487 protein |
Information sourced from Uniprot.org