Human MMP19 protein (Recombinant) (N-His) (STJP005890)

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STJP005890
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MMP19-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MMP19
Gene ID: 4327
Uniprot ID: MMP19_HUMAN
Immunogen Region: Tyr98-Tyr508
Immunogen: Homo sapiens (Human)
Post Translational Modifications Activated by autolytic cleavage after Lys-97. Tyrosine phosphorylated by PKDCC/VLK.
Function Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
Protein Name Matrix Metalloproteinase-19
Mmp-19
Matrix Metalloproteinase Rasi
Matrix Metalloproteinase-18
Mmp-18
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1474228
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Matrix Metalloproteinase-19 protein
Mmp-19 protein
Matrix Metalloproteinase Rasi protein
Matrix Metalloproteinase-18 protein
Mmp-18 protein
MMP19 protein
MMP18 protein
RASI protein

Information sourced from Uniprot.org

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