| Short Description : | Recombinant-Active-Human MMP15-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to cleave a fluorogenic peptide substrate Mca-KPLGL-Dpa-AR-NH2. The specific activity is >200 pmol/min/Mu g, as measured under the described conditions. |
| Gene Symbol: | MMP15 |
| Gene ID: | 4324 |
| Uniprot ID: | MMP15_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Glu47-Pro565 |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. |
| Protein Name | Matrix Metalloproteinase-15Mmp-15Membrane-Type Matrix Metalloproteinase 2Mt-Mmp 2Mtmmp2Membrane-Type-2 Matrix MetalloproteinaseMt2-MmpMt2mmpSmcp-2 |
| Database Links | Reactome: R-HSA-1442490Reactome: R-HSA-1474228Reactome: R-HSA-1592389 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinExtracellular Side |
| Alternative Protein Names | Matrix Metalloproteinase-15 proteinMmp-15 proteinMembrane-Type Matrix Metalloproteinase 2 proteinMt-Mmp 2 proteinMtmmp2 proteinMembrane-Type-2 Matrix Metalloproteinase proteinMt2-Mmp proteinMt2mmp proteinSmcp-2 proteinMMP15 protein |
Information sourced from Uniprot.org