Human MMP1 protein (Recombinant) (N-His) (STJP003632)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP003632
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General Information

Short DescriptionRecombinant-Human MMP1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolMMP1
Gene ID4312
Uniprot IDMMP1_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionPhe20-Asn469

Additional Info

Function Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
Protein Name Interstitial Collagenase
Fibroblast Collagenase
Matrix Metalloproteinase-1
Mmp-1 Cleaved Into - 22 Kda Interstitial Collagenase - 27 Kda Interstitial Collagenase
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1474228
Reactome: R-HSA-1592389
Reactome: R-HSA-210991
Reactome: R-HSA-381426
Reactome: R-HSA-6785807
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Interstitial Collagenase protein
Fibroblast Collagenase protein
Matrix Metalloproteinase-1 protein
Mmp-1 Cleaved Into - 22 Kda Interstitial Collagenase - 27 Kda Interstitial Collagenase protein
MMP1 protein
CLG protein

Information sourced from Uniprot.org

Citations

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