Human MIXL1 protein (Recombinant) (N-GST & C-His) (STJP008844)

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STJP008844
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MIXL1-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MIXL1
Gene ID: 83881
Uniprot ID: MIXL1_HUMAN
Immunogen Region: Ser94-Gly146
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated at multiple sites.
Function Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression.
Protein Name Homeobox Protein Mixl1
Homeodomain Protein Mix
Hmix
Mix1 Homeobox-Like Protein 1
Mix.1 Homeobox-Like Protein
Database Links Reactome: R-HSA-9754189
Reactome: R-HSA-9823730
Cellular Localisation Nucleus
Alternative Protein Names Homeobox Protein Mixl1 protein
Homeodomain Protein Mix protein
Hmix protein
Mix1 Homeobox-Like Protein 1 protein
Mix.1 Homeobox-Like Protein protein
MIXL1 protein
MIXL protein

Information sourced from Uniprot.org

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