Human Max protein (Recombinant) (His-Tag) (STJP016679)

Name: Human Max protein (Recombinant) (His-Tag) (STJP016679)
SKU: STJP016679
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP016679

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Short Description	Recombinant-Human Max-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	MAX
Gene ID	4149
Uniprot ID	MAX_HUMAN
Accession Number	NP_002373.3
Immunogen	Human
Immunogen Region	1-160aa
Immunogen Sequence	MSDNDDIEVE SDEEQPRFQS AADKRAHHNA LERKRRDHIK DSFHSLRDSV PSLQGEKASR AQILDKATEY IQYMRRKNHT HQQDIDDLKR QNALLEQQVR ALEKARSSAQ LQTNYPSSDN SLYTNAKGST ISAFDGGSDS SSESEPEEPQ SRKKLRMEAS

Tissue Specificity	High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.
Post Translational Modifications	Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes.
Function	Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CACGATG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements.
Protein Name	Protein Max Class D Basic Helix-Loop-Helix Protein 4 Bhlhd4 Myc-Associated Factor X
Database Links	Reactome: R-HSA-1362277 Reactome: R-HSA-69202 Reactome: R-HSA-69656 Reactome: R-HSA-8953750
Cellular Localisation	Nucleus Cell Projection Dendrite
Alternative Protein Names	Protein Max protein Class D Basic Helix-Loop-Helix Protein 4 protein Bhlhd4 protein Myc-Associated Factor X protein MAX protein BHLHD4 protein

Information sourced from Uniprot.org