Human MAST2 protein (Recombinant) (N-GST) (STJP005583)

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STJP005583
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MAST2-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MAST2
Gene ID: 23139
Uniprot ID: MAST2_HUMAN
Immunogen Region: Phe512-Phe785
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. N-terminal phosphorylation appears to be a prerequisite for ubiquitination.
Function Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation.
Protein Name Microtubule-Associated Serine/Threonine-Protein Kinase 2
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Recruited To The Sub-Membranous Area On Interaction With Cdhr2
Alternative Protein Names Microtubule-Associated Serine/Threonine-Protein Kinase 2 protein
MAST2 protein
KIAA0807 protein
MAST205 protein

Information sourced from Uniprot.org