Name: Human LMIR1/CD300a protein (Recombinant) (C-hFc&His) (STJP001034)
SKU: STJP001034
Availability: InStock

Human LMIR1/CD300a protein (Recombinant) (C-hFc&His) (STJP001034)

SKU:

STJP001034

£97.50 - £291.50

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	< 0.1 EU/Mu g of the protein by LAL method.

Gene Symbol:	CD300A
Gene ID:	11314
Uniprot ID:	CLM8_HUMAN
Immunogen:	Recombinant Human LMIR1/CD300a Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu 18-Gln 178 ) of human CD300A (Accession #NP_009192.2) fused with an Fc, 6×His tag at the C-terminus.
Immunogen Sequence:	LSKCRTVAGPVGGSLSVQCP YEKEHRTLNKYWCRPPQIFL CDKIVETKGSAGKRNGRVSI RDSPANLSFTVTLENLTEED AGTYWCGVDTPWLRDFHDPV VEVEVSVFPASTSMTPASIT AAKTSTITTAFPPVSSTTLF AVGATHSASIQEETEEVVNS Q

Post Translational Modifications	Phosphorylated on tyrosine. N-glycosylated.
Function	Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.
Protein Name	Cmrf35-Like Molecule 8 Clm-8 Cd300 Antigen-Like Family Member A Cmrf-35-H9 Cmrf35-H9 Cmrf35-H Irc1/Irc2 Immunoglobulin Superfamily Member 12 Igsf12 Inhibitory Receptor Protein 60 Irp60 Nk Inhibitory Receptor Cd Antigen Cd300a
Database Links	Reactome: R-HSA-198933 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Cmrf35-Like Molecule 8 protein Clm-8 protein Cd300 Antigen-Like Family Member A protein Cmrf-35-H9 protein Cmrf35-H9 protein Cmrf35-H protein Irc1/Irc2 protein Immunoglobulin Superfamily Member 12 protein Igsf12 protein Inhibitory Receptor Protein 60 protein Irp60 protein Nk Inhibitory Receptor protein Cd Antigen Cd300a protein CD300A protein CMRF35H protein IGSF12 protein HSPC083 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP001356	Human ROBO4 protein (Recombinant) (C-hFc&His) (STJP001356)	HEK293 cells
STJP001047	Human SECTM1 protein (Recombinant) (C-hFc&His) (STJP001047)	HEK293 cells
STJP001074	Human CD44 protein (Recombinant) (C-hFc&His) (STJP001074)	HEK293 cells
STJP000960	Human EphA3 protein (Recombinant) (C-hFc&His) (STJP000960)	HEK293 cells
STJP000976	Human TYRO3 protein (Recombinant) (C-hFc&His) (STJP000976)	HEK293 cells

Human LMIR1/CD300a protein (Recombinant) (C-hFc&His) (STJP001034)