Human LMIR1/CD300a protein (Recombinant) (C-hFc&His) (STJP001034)

SKU:

STJP001034

$103.28 - $335.48

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human LMIR1/CD300a-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.

Formulation:

Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.

Gene Symbol:	CD300A
Gene ID:	11314
Uniprot ID:	CLM8_HUMAN
Immunogen:	Recombinant Human LMIR1/CD300a Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Leu 18-Gln 178 ) of human CD300A (Accession #NP_009192.2) fused with an Fc, 6×His tag at the C-terminus.

Post Translational Modifications	Phosphorylated on tyrosine. N-glycosylated.
Function	Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.
Protein Name	Cmrf35-Like Molecule 8 Clm-8 Cd300 Antigen-Like Family Member A Cmrf-35-H9 Cmrf35-H9 Cmrf35-H Irc1/Irc2 Immunoglobulin Superfamily Member 12 Igsf12 Inhibitory Receptor Protein 60 Irp60 Nk Inhibitory Receptor Cd Antigen Cd300a
Database Links	Reactome: R-HSA-198933 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Cmrf35-Like Molecule 8 protein Clm-8 protein Cd300 Antigen-Like Family Member A protein Cmrf-35-H9 protein Cmrf35-H9 protein Cmrf35-H protein Irc1/Irc2 protein Immunoglobulin Superfamily Member 12 protein Igsf12 protein Inhibitory Receptor Protein 60 protein Irp60 protein Nk Inhibitory Receptor protein Cd Antigen Cd300a protein CD300A protein CMRF35H protein IGSF12 protein HSPC083 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance