Human LAMP3 protein (Recombinant) (N-His) (STJP016338)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human LAMP3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | LAMP3 |
| Gene ID | 27074 |
| Uniprot ID | LAMP3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser222-Cys376 |
Additional Info
| Function | Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity. (Microbial infection) Plays a positive role in post-entry steps of influenza A virus replication, either virus uncoating, cytosolic transport, or nuclear import of viral components, and promotes nuclear accumulation of influenza nucleoprotein/NP at early stages of viral infection. (Microbial infection) Supports the FURIN-mediated cleavage of mumps virus fusion protein F by interacting with both FURIN and the unprocessed form but not the processed form of the viral protein F. (Microbial infection) Promotes the intracellular proliferation of Salmonella typhimuium. |
| Protein Name | Lysosome-Associated Membrane Glycoprotein 3Lamp-3Lysosomal-Associated Membrane Protein 3Dc-Lysosome-Associated Membrane GlycoproteinDc LampProtein Tsc403Cd Antigen Cd208 |
| Database Links | |
| Cellular Localisation | Cell SurfaceLysosome MembraneSingle-Pass Type I Membrane ProteinCytoplasmic Vesicle MembraneEarly Endosome MembraneDuring Dendritic Cell MaturationDetected On Cytoplasmic Vesicles (The Mhc Ii Compartment) That Contain Mhc Ii ProteinsLamp1Lamp2 And Lamp3Detected On Lysosomes In Mature Dendritic Cells |
| Alternative Protein Names | Lysosome-Associated Membrane Glycoprotein 3 proteinLamp-3 proteinLysosomal-Associated Membrane Protein 3 proteinDc-Lysosome-Associated Membrane GlycoproteinDc Lamp proteinProtein Tsc403 proteinCd Antigen Cd208 proteinLAMP3 proteinDCLAMP proteinTSC403 protein |
Information sourced from Uniprot.org