Human KLRG1 protein (Recombinant) (His-Tag) (STJP017993)

SKU:
STJP017993
£134.50 - £738.50
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Short Description :Recombinant-Human KLRG1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Denatured
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:KLRG1
Gene ID:10219
Uniprot ID:KLRG1_HUMAN
Accession Number:NP_005801.3
Immunogen:Human
Immunogen Region:60-189aa
Immunogen Sequence:LCQGSNY STCASCPSCP DRWMKYGNHC YYFSVEEKDW NSSLEFCLAR DSHLLVITDN QEMSLLQVFL SEAFCWIGLR NNSGWRWEDG SPLNFSRISS NSFVQTCGAI NKNGLQASSC EVPLHWVCKK VRL
Tissue Specificity Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
Function Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
Protein Name Killer Cell Lectin-Like Receptor Subfamily G Member 1
C-Type Lectin Domain Family 15 Member A
Itim-Containing Receptor Mafa-L
Mafa-Like Receptor
Mast Cell Function-Associated Antigen
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Killer Cell Lectin-Like Receptor Subfamily G Member 1 protein
C-Type Lectin Domain Family 15 Member A protein
Itim-Containing Receptor Mafa-L protein
Mafa-Like Receptor protein
Mast Cell Function-Associated Antigen protein
KLRG1 protein
CLEC15A protein
MAFA protein
MAFAL protein

Information sourced from Uniprot.org