Human KLRG1 protein (Recombinant) (His-Tag) (STJP017993)

Name: Human KLRG1 protein (Recombinant) (His-Tag) (STJP017993)
SKU: STJP017993
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017993

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Short Description	Recombinant-Human KLRG1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE/Denatured
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	KLRG1
Gene ID	10219
Uniprot ID	KLRG1_HUMAN
Accession Number	NP_005801.3
Immunogen	Human
Immunogen Region	60-189aa
Immunogen Sequence	LCQGSNY STCASCPSCP DRWMKYGNHC YYFSVEEKDW NSSLEFCLAR DSHLLVITDN QEMSLLQVFL SEAFCWIGLR NNSGWRWEDG SPLNFSRISS NSFVQTCGAI NKNGLQASSC EVPLHWVCKK VRL

Tissue Specificity	Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
Function	Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
Protein Name	Killer Cell Lectin-Like Receptor Subfamily G Member 1 C-Type Lectin Domain Family 15 Member A Itim-Containing Receptor Mafa-L Mafa-Like Receptor Mast Cell Function-Associated Antigen
Database Links	Reactome: R-HSA-198933
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein
Alternative Protein Names	Killer Cell Lectin-Like Receptor Subfamily G Member 1 protein C-Type Lectin Domain Family 15 Member A protein Itim-Containing Receptor Mafa-L protein Mafa-Like Receptor protein Mast Cell Function-Associated Antigen protein KLRG1 protein CLEC15A protein MAFA protein MAFAL protein

Information sourced from Uniprot.org