| Short Description : | Recombinant-Human KLRG1/CLEC15A/CD369-N-raFc protein was developed in hek293 cells using the region Leu60-Phe195. For use in research applications. |
| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Gene Symbol: | KLRG1 |
| Gene ID: | 10219 |
| Uniprot ID: | KLRG1_HUMAN |
| Immunogen: | Recombinant Human KLRG1/CLEC15A/CD369 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu60-Phe195) of human KLRG1/CLEC15A/CD369 (Accession #NP_001316028.1) fused with a raFc tag at the N-terminus |
| Immunogen Region: | Leu60-Phe195 |
| Immunogen Sequence: | LCQGSNYSTCASCPSCPDRW MKYGNHCYYFSVEEKDWNSS LEFCLARDSHLLVITDNQEM SLLQVFLSEAFCWIGLRNNS GWRWEDGSPLNFSRISSNSF VQTCGAINKNGLQASSCEVP LHWVCKKCPFADQALF |
| Function | Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. |
| Protein Name | Killer Cell Lectin-Like Receptor Subfamily G Member 1C-Type Lectin Domain Family 15 Member AItim-Containing Receptor Mafa-LMafa-Like ReceptorMast Cell Function-Associated Antigen |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Killer Cell Lectin-Like Receptor Subfamily G Member 1 proteinC-Type Lectin Domain Family 15 Member A proteinItim-Containing Receptor Mafa-L proteinMafa-Like Receptor proteinMast Cell Function-Associated Antigen proteinKLRG1 proteinCLEC15A proteinMAFA proteinMAFAL protein |
Information sourced from Uniprot.org
