• Human KLRG1/CLEC15A/CD369 protein (Recombinant) (N-raFc) (STJP001515)

Human KLRG1/CLEC15A/CD369 protein (Recombinant) (N-raFc) (STJP001515)

SKU:
STJP001515

£72.50 - £223.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human KLRG1/CLEC15A/CD369-N-raFc protein was developed from hek293 cells and has a target region of N-raFc. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Gene Symbol: KLRG1
Gene ID: 10219
Uniprot ID: KLRG1_HUMAN
Immunogen: Recombinant Human KLRG1/CLEC15A/CD369 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu60-Phe195) of human KLRG1/CLEC15A/CD369 (Accession #NP_001316028.1) fused with a raFc tag at the N-terminus
Function Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
Protein Name Killer Cell Lectin-Like Receptor Subfamily G Member 1
C-Type Lectin Domain Family 15 Member A
Itim-Containing Receptor Mafa-L
Mafa-Like Receptor
Mast Cell Function-Associated Antigen
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Killer Cell Lectin-Like Receptor Subfamily G Member 1 protein
C-Type Lectin Domain Family 15 Member A protein
Itim-Containing Receptor Mafa-L protein
Mafa-Like Receptor protein
Mast Cell Function-Associated Antigen protein
KLRG1 protein
CLEC15A protein
MAFA protein
MAFAL protein

Information sourced from Uniprot.org

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