Function | Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. |
Protein Name | Killer Cell Lectin-Like Receptor Subfamily G Member 1C-Type Lectin Domain Family 15 Member AItim-Containing Receptor Mafa-LMafa-Like ReceptorMast Cell Function-Associated Antigen |
Database Links | Reactome: R-HSA-198933 |
Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Protein Names | Killer Cell Lectin-Like Receptor Subfamily G Member 1 proteinC-Type Lectin Domain Family 15 Member A proteinItim-Containing Receptor Mafa-L proteinMafa-Like Receptor proteinMast Cell Function-Associated Antigen proteinKLRG1 proteinCLEC15A proteinMAFA proteinMAFAL protein |
Information sourced from Uniprot.org