Human KLF3 protein (Recombinant) (His-Tag) (STJP018353)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018353
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General Information

Short DescriptionRecombinant-Human KLF3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Denatured
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolKLF3
Gene ID51274
Uniprot IDKLF3_HUMAN
Accession NumberNP_057615
ImmunogenHuman
Immunogen Region1-345aa
Immunogen SequenceMLMFDPV PVKQEAMDPV SVSYPSNYME SMKPNKYGVI YSTPLPEKFF QTPEGLSHGI QMEPVDLTVN KRSSPPSAGN SPSSLKFPSS HRRASPGLSM PSSSPPIKKY SPPSPGVQPF GVPLSMPPVM AAALSRHGIR SPGILPVIQP VVVQPVPFMY TSHLQQPLMV SLSEEMENSS SSMQVPVIES YEKPISQKKI KIEPGI

Additional Info

Post Translational Modifications Sumoylated with SUMO1. Sumoylation is enhanced by PIAS1, PIAS2alpha and PIAS2beta, and PIAS4, but not by Pc2. Enhances transcriptional repression, but has no effect on DNA binding. Sumoylation on Lys-198 is the major site.
Function Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis.
Protein Name Krueppel-Like Factor 3
Basic Krueppel-Like Factor
Caccc-Box-Binding Protein Bklf
Tef-2
Database Links
Cellular Localisation Nucleus
Alternative Protein Names Krueppel-Like Factor 3 protein
Basic Krueppel-Like Factor protein
Caccc-Box-Binding Protein Bklf protein
Tef-2 protein
KLF3 protein
BKLF protein

Information sourced from Uniprot.org

Citations

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