Human KIR3DL2/CD158k protein (Recombinant) (C-His&Avi) (STJP020310)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human KIR3DL2/CD158k Protein is produced by Expi293 cells expression system. The target protein is expressed with sequence (Leu22-Leu339) of Human KIR3DL2/CD158k (Accession #P43630-1) fused with His tag and Avi tag at the C-terminus.
General Information
| Short Description | Recombinant-Human KIR3DL2/CD158k-C-His&Avi protein was developed in hek293 cells using the region Leu22-Leu339. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | KIR3DL2 |
| Gene ID | 3812 |
| Uniprot ID | KI3L2_HUMAN |
| Immunogen | Recombinant Human KIR3DL2/CD158k Protein is produced by Expi293 cells expression system. The target protein is expressed with sequence (Leu22-Leu339) of Human KIR3DL2/CD158k (Accession #P43630-1) fused with His tag and Avi tag at the C-terminus. |
| Immunogen Region | Leu22-Leu339 |
Additional Info
| Tissue Specificity | Expressed in astrocytes. |
| Function | Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3dl2Cd158 Antigen-Like Family Member KNatural Killer-Associated Transcript 4Nkat-4P70 Natural Killer Cell Receptor Clone Cl-5P70 Nk Receptor Cl-5Cd Antigen Cd158k |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Killer Cell Immunoglobulin-Like Receptor 3dl2 proteinCd158 Antigen-Like Family Member K proteinNatural Killer-Associated Transcript 4 proteinNkat-4 proteinP70 Natural Killer Cell Receptor Clone Cl-5 proteinP70 Nk Receptor Cl-5 proteinCd Antigen Cd158k proteinKIR3DL2 proteinCD158K proteinNKAT4 protein |
Information sourced from Uniprot.org