Human ITPA protein (Recombinant) (C-His) (STJP014687)

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STJP014687-100
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Short Description :Recombinant-Human ITPA-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications.
Applications:ELISA/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Formulation:Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 5% Trehalose, 300mM NaCl, 30% Glycerol, 0.05% Tween 80, pH 8.0.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:ITPA
Gene ID:3704
Uniprot ID:ITPA_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ala2-Ala194
Function Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
Protein Name Inosine Triphosphate Pyrophosphatase
Itpase
Inosine Triphosphatase
Non-Canonical Purine Ntp Pyrophosphatase
Non-Standard Purine Ntp Pyrophosphatase
Nucleoside-Triphosphate Diphosphatase
Nucleoside-Triphosphate Pyrophosphatase
Ntpase
Putative Oncogene Protein Hlc14-06-P
Xtp/Ditp Diphosphatase
Database Links Reactome: R-HSA-74259
Reactome: R-HSA-9755088
Cellular Localisation Cytoplasm
Alternative Protein Names Inosine Triphosphate Pyrophosphatase protein
Itpase protein
Inosine Triphosphatase protein
Non-Canonical Purine Ntp Pyrophosphatase protein
Non-Standard Purine Ntp Pyrophosphatase protein
Nucleoside-Triphosphate Diphosphatase protein
Nucleoside-Triphosphate Pyrophosphatase protein
Ntpase protein
Putative Oncogene Protein Hlc14-06-P protein
Xtp/Ditp Diphosphatase protein
ITPA protein
C20orf37 protein
My049 protein
OK protein
SW-cl.9 protein

Information sourced from Uniprot.org