Human ITPA protein (Recombinant) (C-His) (STJP014687)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ITPA-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 5% Trehalose, 300mM NaCl, 30% Glycerol, 0.05% Tween 80, pH 8.0. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | ITPA |
| Gene ID | 3704 |
| Uniprot ID | ITPA_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala2-Ala194 |
Additional Info
| Function | Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. |
| Protein Name | Inosine Triphosphate PyrophosphataseItpaseInosine TriphosphataseNon-Canonical Purine Ntp PyrophosphataseNon-Standard Purine Ntp PyrophosphataseNucleoside-Triphosphate DiphosphataseNucleoside-Triphosphate PyrophosphataseNtpasePutative Oncogene Protein Hlc14-06-PXtp/Ditp Diphosphatase |
| Database Links | Reactome: R-HSA-74259Reactome: R-HSA-9755088 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Inosine Triphosphate Pyrophosphatase proteinItpase proteinInosine Triphosphatase proteinNon-Canonical Purine Ntp Pyrophosphatase proteinNon-Standard Purine Ntp Pyrophosphatase proteinNucleoside-Triphosphate Diphosphatase proteinNucleoside-Triphosphate Pyrophosphatase proteinNtpase proteinPutative Oncogene Protein Hlc14-06-P proteinXtp/Ditp Diphosphatase proteinITPA proteinC20orf37 proteinMy049 proteinOK proteinSW-cl.9 protein |
Information sourced from Uniprot.org