Human IL5 (Interleukin-5) Sandwich ELISA Kit (STJE0000021)
SPECIFICATIONS
ConjugationBiotin
General Information
| Short Description | This Interleukin-5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma and cell culture supernates. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.43 pg/mL |
| Detection Limit | 156-100 pg/ml |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Storage Instruction | Unopened kits can be stored at 2-8°C for 1 year, and opened products must be used within 1 month. |
| Assay Time | 4 hours |
| Detection | Colorimetric |
Target Information
| Gene Symbol | IL5 |
| Gene ID | 3567 |
| Uniprot ID | IL5_HUMAN |
| Sample Type | serum, plasma and cell culture supernates |
Additional Info
| Tissue Specificity | Present in peripheral blood mononuclear cells. |
| Post Translational Modifications | |
| Function | Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively. |
| Protein Name | Interleukin-5Il-5B-Cell Differentiation Factor IEosinophil Differentiation FactorT-Cell Replacing FactorTrf |
| Database Links | Reactome: R-HSA-512988Reactome: R-HSA-5673001Reactome: R-HSA-912526 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Interleukin-5 ELISA kitIl-5 ELISA kitB-Cell Differentiation Factor I ELISA kitEosinophil Differentiation Factor ELISA kitT-Cell Replacing Factor ELISA kitTrf ELISA kitIL5 ELISA kit |
| output |
Information sourced from Uniprot.org