Human IL31RA protein (Recombinant) (C-His) (STJP007118)

Name: Human IL31RA protein (Recombinant) (C-His) (STJP007118)
SKU: STJP007118
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ImmunogenHomo sapiens (Human)

STJP007118

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Short Description	Recombinant-Human IL31RA-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	N-glycosylated.
Function	Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro.
Protein Name	Interleukin-31 Receptor Subunit Alpha Il-31 Receptor Subunit Alpha Il-31r Subunit Alpha Il-31r-Alpha Il-31ra Cytokine Receptor-Like 3 Glm-R Hglm-R Gp130-Like Monocyte Receptor Gp130-Like Receptor Zcytor17
Database Links	Reactome: R-HSA-6788467
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Presynaptic Cell Membrane Cell Projection Axon
Alternative Protein Names	Interleukin-31 Receptor Subunit Alpha protein Il-31 Receptor Subunit Alpha protein Il-31r Subunit Alpha protein Il-31r-Alpha protein Il-31ra protein Cytokine Receptor-Like 3 protein Glm-R protein Hglm-R protein Gp130-Like Monocyte Receptor protein Gp130-Like Receptor protein Zcytor17 protein IL31RA protein CRL3 protein GPL protein UNQ6368 protein PRO21073 protein PRO21384 protein

Information sourced from Uniprot.org