Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human IL-7 receptor (CD127)-protein was developed from hek293. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Immunoreactivity: | Recombinant Human IL-7 receptor alpha (CD127) Activity was determined by its binding ability of biotinylated mouse TSLP in a functional ELISA. NA |
Gene Symbol: | IL7R |
Gene ID: | 3575 |
Uniprot ID: | IL7RA_HUMAN |
Immunogen Region: | ECD |
Immunogen: | Optimized DNA sequence encoding extracellular domain of Human IL-7 receptor alpha including a C-terminal His tag was expressed in HEK293 cells. NA |
Post Translational Modifications | N-glycosylated IL-7Ralpha binds IL7 300-fold more tightly than the unglycosylated form. |
Function | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
Protein Name | Interleukin-7 Receptor Subunit Alpha Il-7 Receptor Subunit Alpha Il-7r Subunit Alpha Il-7r-Alpha Il-7ra Cdw127 Cd Antigen Cd127 |
Database Links | Reactome: R-HSA-1266695 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 |
Cellular Localisation | Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Isoform 3: Cell Membrane Isoform 4: Secreted |
Alternative Protein Names | Interleukin-7 Receptor Subunit Alpha protein Il-7 Receptor Subunit Alpha protein Il-7r Subunit Alpha protein Il-7r-Alpha protein Il-7ra protein Cdw127 protein Cd Antigen Cd127 protein IL7R protein |
Information sourced from Uniprot.org